One In a Million
Select one in a million with ease
A common way of performing high-throughput screening experiments is to utilize robotic liquid
handlers. However, despite their versatility, typical robotic workflows are limited in throughput
when it comes to functional assays. To overcome this we have developed the Sapphire platform, which
allows to screen millions of functional assays in a single day with ease.
We have designed the Sapphire platform to be compatible with
different functional assays.
Screen massive libraries of cells and recover them based on their
In Vitro Evolution
Steer proteins towards desired traits and select the most
suitable variants from massive libraries
Make the design-build-test cycle faster and select desired
variants out of massive libraries.
The Sapphire platform utilizes droplet microfluidic technology and is
compatible with various functional
screening assays. No matter what your library size and screening complexity are, you can achieve it with the
Droplet microfluidics allows for these ultrahigh rates for both screening and
manipulations, positioning droplet technology as a strong contender for the next generation of
chemical and biochemical HTS and experimentation methods.
Droplet microfluidics achieves ultrahigh screening rates by compartmentalizing reactions to high
pL volume droplets. This allows libraries with as large as 108-109 variants to
easily screened in short
periods of time. Droplets can also be selected by their fluorescence to select targeted populations