“With the arrival of the microfluidic instrument ONYX, our custom single-cell workflows have taken a major leap forward in their sophistication, ease of deployment, and data quality.
The Droplet Genomics team has provided superb training and support as we have migrated to their open-ended systems and protocols. For both newcomers and veteran users of droplet methods, microfluidic company Droplet Genomics delivers an incredible product that we cannot recommend highly enough!"
EASIER DISCOVERIES WITH DROPLET GENERATOR
ONYX makes droplet generation and manipulation effortless.
ONYX droplet generator combines pumps, microscope, high-speed camera and high-voltage power source into an easy-to-use package that is a complete solution for any lab wanting to adopt the droplet microfluidics technology.

START YOUR DROPLET MICROFLUIDICS
RESEARCH NOW
The easy way to run your single-cell/molecule experiments
YOUR EXPERIMENT - YOUR RULES
Nobody knows your experiment design better than you

DROPLET GENERATOR ONYX CAPABILITIES
Easy droplet generation and manipulation
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Generate
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Inject
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Merge
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Mix
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Store
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Split
DROPLET GENERATOR ONYX RELATED RESOURCES
Learn more
ALL-IN-ONE DROPLET MICROFLUIDIC INSTRUMENT
Your easy-to-use spaceship to the galaxies within the inner cosmos



MICROFLUIDIC SYSTEM
FEATURES
- 01 Small footprint
- 02 High-speed microscopy
- 03 No chip lock-in
- 04 Integrated forcefield generator
- 05 Embedded UI software
- 06 Open API
- 07 In-line droplet analysis
- 08 650nm monochromatic illumination
MICROFLUIDIC SYSTEM SPECIFICATIONS
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Sample handling
4x syringe pumps
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High-speed imaging
Up to 4k FPS
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Droplet analysis
Image-based
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Active manipulation
Enabled by forcefield generator module
Microfluidic instrument ONYX related downloads:

PROFESSIONAL SUPPORT
No need for an FAQ, the help is one call away
Trusted by researchers
Daniel E. Wagner, Ph.D.
Assistant Professor
University of California, San Francisco
Assistant Professor
University of California, San Francisco

"Orbit Discovery generates peptide libraries on the magnitude of millions or even billions of peptides but has been hindered by an ability to screen just 10,000 to 50,000 select peptides at a time using wells on plates. Our prime focus has been trying to identify new technologies that would allow us to smash through that barrier of limitation.
The STYX platform allowed us to make a quantum leap in terms of numbers and throughput. We can screen millions or even up to tens of millions of variants with this technology. There is not much else out there with similar capabilities. This has been a breakthrough technology product for us."
The STYX platform allowed us to make a quantum leap in terms of numbers and throughput. We can screen millions or even up to tens of millions of variants with this technology. There is not much else out there with similar capabilities. This has been a breakthrough technology product for us."
Anthony Pitt
CTO
Orbit Discovery
CTO
Orbit Discovery

"Droplet Genomics has been instrumental in the launch of our custom microfluidics pipeline. Droplet Genomics provided excellent support and training to get us up-and-running quickly and helped refine our pipeline using their deep technical expertise. They are fun and easy to work with and consistently deliver a reliable product every time. Whether you are a newcomer or experienced user, Droplet Genomics is an incredible company to work with that I highly recommend!"
Dorothy Koveal, Ph.D.
Postdoctoral Associate
Harvard Medical School, Boston, MA
Postdoctoral Associate
Harvard Medical School, Boston, MA

"Droplet Genomics has been a fantastic partner. We purchased Onyx, as well as Styx and are using their chips and reagents on a regular basis. Their instruments are cutting-edge and extremely user-friendly. But above all is their support and flexibility. Droplets Genomics are real experts in what they do and they provided us with invaluable consultations in the beginning. They are a trusted partner I would recommend to anyone in the field."
Algirdas Toleikis, Ph.D.
Head of Engineering
Delta Biosciences
Head of Engineering
Delta Biosciences

"Conducting large-scale atlasing projects on a DIY single-cell platform has presented us with a number of challenges, often more logistical than technical. Droplet Genomics has been instrumental to our research by supplying us with the tools we need to keep our projects moving forward during uncertain times. The quality and consistency of their devices gives us peace of mind and allows us to focus on the more pressing variables in our experiments. The products, services, and innovations they provide are an asset to the droplet microfluidics community."
Joey Simmons
Sr. Research Specialist
Lau Lab, Vanderbilt University
Sr. Research Specialist
Lau Lab, Vanderbilt University

"Our ONYX was installed in 2020 by the head of engineering at Droplet Genomics. Training provided at that time and the customer service we've experienced ever since has been nothing less than stellar. Whenever we've encountered an obstacle or have a question or suggestion and reached out to them, they've responded in such a timely manner that it's hard to know we are on separate continents. The Droplet Genomics team actively listens, and if there is something they can do to improve the operator's experience they prioritize actions accordingly. This high quality service for a product that operates as advertised is everything you could possibly want from a microfluidics company."
Brian Thompson
Senior Research Associate
Bigelow Laboratory for Ocean Sciences
Senior Research Associate
Bigelow Laboratory for Ocean Sciences

"For years, I'd been hoping that someone would make an instrument like the Styx. Droplet Genomics finally did and they did not disappoint. The compact and fully contained instrument performs as well as a traditional optical table based system. Furthermore, the robust hardware and very intuitive software, along with their excellent customer and technical support, erase a lot of the headaches involved with droplet microfluidics. Highly recommend for anyone using or planning to use droplet microfluidics in their workflow."
Tom Curtis, PhD
Senior Research Scientist
Antimicrobial Discovery Center
Northeastern University
Senior Research Scientist
Antimicrobial Discovery Center
Northeastern University


ULTIMATE DROPLET MICROFLUIDICS SETUP
Advance your high-throughput screening workflows with
Droplet Genomics instrument combo
Droplet Genomics instrument combo
Sample encapsulation
Droplet merging
Pico-injection
Droplet selection
Positive hits
Negative hits
Droplet generator
and manipulator
and manipulator
Fluorescence-activated
droplet sorting
droplet sorting
Droplet generator and manipulator
Sample encapsulation
Droplet merging
Pico-injection
Positive hits
Negative hits
Droplet selection
Fluorescence-activated droplet sorting